Research
Dr. Mechanic is an active participant in cutting-edge research. He is an associate editor of the Journal of Internal and Emergency Medicine.
Current projects include:
GAMEFILM: Using CTA Measures to Define Cardiac Risk in NFL Alumni.
Heartlung.AI: AI-powered disease detection technology that analyzes low-dose CT scans to provide FDA-cleared personalized prevention results.
Prior grants include: Harvard Medical School Eleanor and Miles Shore Award (Clinical innovation), Infectious Disease Society of America (HIV and lymphoma, Malawi)
Publications
Dr. Mechanic has co-authored 30+ manuscripts, cited over 2000 times in the medical literature. Notable mentions include:
Peripheral Vasopressor Use in Early-Sepsis Induced Hypotension. NIH PETAL Network. JAMA Open. 2025.
ChatGPT passing USMLE shines a spotlight on the flaws of medical education. AB Mbakwe, I Lourentzou, LA Celi, OJ Mechanic, A Dagan. PLOS. 2024. (Cited >300)
Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension. NIH PETAL Network. New England Journal of Medicine. 2023.
Administration of anti–SARS-CoV-2 monoclonal antibodies after US food and drug administration deauthorization. T Anderson, A O’Donoghue, O Mechanic, T Dechen, J Stevens. JAMA Open. 2022
Syncope and Related Paroxysmal Spells. O Mechanic, S Grossman. 2018.
Acute Myocardial Infarction. O Mechanic, S Grossman. 2017. (Cited >300)
Southern diets differ from others and may explain an increased risk of obesity. O Mechanic. Wilson Library, UNC Chapel Hill. 2009.
Teaching
Dr. Mechanic is an associate professor of medical education, emergency medicine, and critical care. He was previously core faculty at Harvard Medical School.
He guest lectures at the University of Miami Business School on health policy and has taught / given grand rounds at: Harvard Medical School, Suffolk Law School, Morehouse School of Medicine, Harvard Executive Education, World of Healthcare (Ministry of Health, Netherlands), and Mount Sinai Medical Center, among other academic institutions.